Austin kicked off via Hawaii, seat of the American military command for the Indo-Pacific region, his first foreign visits as Pentagon chief.
"This is all about alliances and partnerships," he told reporters on the trip that is to include meetings with key allies in Tokyo, New Delhi, and Seoul.
"It's also about enhancing capabilities," he added, recalling that while the United States was focused on the anti-jihadist struggle in the Middle East, China was modernizing its army at high speed.
"That competitive edge that we've had has eroded," he said. "We still maintain that edge. We are going to increase that edge going forward."
"Our goal is to make sure that we have the capabilities and the operational plans… to be able to offer a credible deterrence to China or anybody else who would want to take on the US," he added.
Lloyd will be joined in Tokyo and Seoul by Secretary of State Antony Blinken.
"One of the things that the secretary of state and I want to do is begin to strengthen those alliances," he said. "This will be more about listening and learning, getting their point of view."
This tour in Asia of the heads of diplomacy and defense of the United States follows an unprecedented summit of the "Quad", an informal alliance born in the 2000s to counterbalance a rising China.
Blinken will join President Joe Biden's national security advisor, Jake Sullivan, in Anchorage on March 18 with their Chinese counterparts Wang Yi and Yang Jiechi.
The Alaska talks will be the first between the powers since Yang met Blinken's hawkish predecessor Mike Pompeo in June in Hawaii — a setting similarly far from the high-stakes glare of national capitals.
The Biden administration has generally backed the tougher approach to China initiated by former president Donald Trump, but has also insisted that it can be more effective by shoring up alliances and seeking narrow ways to cooperate on priorities such as climate change.
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